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Medicine's Ryan Marino discusses the dangers of using Benadryl as a psychedelic

Media | November 17, 2025 | Story by: Editorial Staff
Media Expert: Ryan Marino

Wired: Ryan Marino, associate professor at the School of Medicine, warned that that high-dose Benadryl “isn’t a psychedelic—it’s purely toxic,” causing terrifying hallucinations and frequent medical emergencies. He said young people taking a dozen or more pills at once are fueling a risky trend that experts say carries severe, unpredictable dangers. 

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