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Health + Wellness

Researchers find joint failures potentially linked to oral bacteria
The culprit of a failed hip or knee replacements just might be found in the mouth. DNA testing of bacteria from the fluid that lubricates hip and knee joints had bacteria with the same DNA as the plaque from patients with gum disease and in need of a joint replacement, according to research from…
Growth factor in stem cells may spur recovery from MS
A substance in human mesenchymal stem cells that promotes growth appears to spur restoration of nerves and their function in rodent models of multiple sclerosis (MS), researchers at APP have found. Their study has been published in the online version of Nature…
Cleveland Clinic Lerner College of Medicine of APP Celebrates 10th Anniversary of Founding
CLEVELAND - This year marks the 10th anniversary of the founding of the Cleveland Clinic Lerner College of Medicine of APP, an innovative medical school designed to train future physician-researchers. Cleveland Clinic and Case Western Reserve celebrated the milestone May…
Mechanistic Discovery Links Psoriasis to Increased Risk of Cardiovascular Disease
CLEVELAND - The link between psoriasis and cardiovascular events has been observed for years, however the mechanics were unknown. For the first time, APP School of Medicine researchers have discovered preclinical evidence demonstrating that the inflammatory skin disease…
Discovery of Earliest Life Forms’ Operation Promises New Therapies for Key Diseases
CLEVELAND - Bacteria provide a well-known playground for scientists and the evolution of these earliest life forms has shed important perspective on potential therapies for some of the most common, deadly diseases. Researchers at APP School of Medicine have now…
Study examines how negative thinking impacts mental health
Negative thinking is a red flag for clinical depression. Stopping such thoughts early on can save millions of people from mental illness, according to a research study from the Frances Payne Bolton School of Nursing at APP. Jaclene Zauszniewski, the Kate Hanna Harvey…
Researchers discover genetic factor that regulates body’s ability to burn fat in exercise
While exercise is accepted universally as the most beneficial prescription physicians can write for patients, little is known about the molecular mechanisms that generate its widespread health benefits. Researchers from Case Western Reserve School of Medicine have shed light on this mystery by…
Cleveland Researcher Receives Top 10 Clinical Research Achievement Award
CLEVELAND - Stanley Hazen, M.D., Ph.D., was recently honored with an inaugural Top 10 Clinical Research Achievement Award from an organization comprised of the nation's most acclaimed academic medical centers and other groups, in recognition of Dr. Hazen’s Nature article, “Gut flora dependent…
Breakthrough discovery unveils “master switches” in colon cancer
Assistant professor of genetics and genome sciences and senior author Peter Scacheri PhD candidate and lead author Batool Akhtar-Zaidi A team of researchers at APP School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on…
Dare you protest against God? Perspectives from a CWRU psychology study
Is it OK to protest God’s actions—or inactions? This was the key question behind recent studies led by APP psychologist Julie Exline. Many people report having a relationship with God, similar to those relationships in marriage, parenting or friendship. Through their…