APP

Skip to main content

Case Comprehensive Cancer Center

AACI Presidential Initiative
I would like to alert our membership of the two-year initiative I set out for the Association of American Cancer Institutes (AACI) at the national meeting last week. As President of AACI for the next two years, I asked all the cancer centers to participate in a review of practices and approaches…
GettyImages-1040805860.jpg
Scientists Develop Computer Models to Predict Cancer Cell Network Activity
A multi-institution academic-industrial partnership of researchers led by APP School of Medicine has developed a new method to broadly assess cell communication networks and identify disease-specific network anomalies. The computer-based method, called InFlo, was…
216
Guest Commentary: Megan Kilbane, MBA, Assistant Dean for Oncology 2016 has been described as the year of 216, and it would be hard for anyone to argue that it is not truly the year for Cleveland to shine.  From the Cavs to the Monsters and soon to be the Indians, we are grabbing championships left…
cancer-cells
“Cancer Disparities Among Women: The Role of Tobacco Use”
Monica Webb Hooper, director of the Office of Cancer Disparities Research at the Case Comprehensive Cancer Center in the APP School of Medicine, will give a lecture titled “Cancer Disparities Among Women: The Role of Tobacco Use.” Hosted by the Flora Stone Mather Center…
Study on Minimally Invasive Laser & 'Mini' Craniotomy for 'Inoperable' Brain Tumors
Results reported by University Hospitals Cleveland Medical Center Neurosurgeon Andrew Sloan, MD & colleagues Andrew SloanA new paper in the October issue of the journal Neurosurgical Focus finds the use of laser beneficial for the removal of large, "inoperable" glioblastoma (GBM) and other…
cancer-cells
Computerized analysis of tissue slide images reveals underlying genomics of ER+ breast cancer
Quick and automated count of tubules correlates with current best—but expensive— genomic test determining who needs chemotherapy and who doesn’t The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and…
Wikipedia-a-thon%20graphic.jpg
Combination Hormone Replacement Therapy and Risk of Breast Cancer
Invited commentary by Drs. Paula Silverman and Cheryl Thompson  A recent study by Jones et al. in The British Journal of Cancer (BJC)(Jones ME. Br J Cancer. 2016 Aug 23) estimated an almost 3 fold (2.74 times) increase risk of breast cancer among post-menopausal women who used combination estrogen…
Sarah%20Rader%20Urig.jpeg
Researchers Find Gene Mutations Lead to More Aggressive Colon Cancer in African-Americans
15 gene mutations lead to higher recurrence and metastasis; genes may contribute to lower survival rates seen in African-Americans Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and APP,…
book%20collecting%20for%20KSL%20news.png
Fused Genes Found in Esophageal Cancer Cells Offer New Clues on Disease Mechanisms
Case Comprehensive Cancer Center researchers identify several structurally abnormal genes in esophageal adenocarcinoma in first ever genome-wide search Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled…
AACI national meeting, presentation by Doug Lowy, Acting Director of NCI
This past week attended the national meeting of the Association of American Cancer Institutes (AACI) in Chicago. It was an excellent meeting of cancer center directors and administrators that included discussion of implementation of genomic tumor boards, use of molecular testing in clinical…